Resultados: 79

Silicone tape versus micropore tape to prevent medical adhesive-related skin injuries: systematic review and meta-analysis

Objective: This study aims to compare the efficacy and safety of silicone tapes compared to microporous tapes in patients with fragile skin. Methods: A systematic review of the scientific literature was carried out. Clinical trials that compared silicone tape for medical use with the microporous tape in ...

Cost-minimization analysis of biological disease-modifying antirheumatic drugs in the Brazilian public health system (SUS) considering patients’ weight

Objective: To perform a cost-minimization analysis comparing the cohort with the current average patient weight of 70 kg (MoH current assumption). Since most rheumatoid arthritis (RA) patients in Brazil are women (60 kg or less), we also aimed to define this percentage at Brazilian public healthcare syst...

Unveiling atopic dermatitis burden in Brazil: a report from clinical assistance perspective

Objective: Atopic dermatitis (AD) or atopic eczema is a chronic skin inflammatory disease that involves the interaction between immune, genetic and environmental triggers. AD affects 15%-20% of infants and 1%-4% of adults worldwide although prevalence varies per country. The main objective is to raise th...

The influence of reproductive information quality on the probability of unplanned and unwanted pregnancies in Brazil

Background: Unplanned pregnancies are a significant risk factor for inadequate use of prenatal care, and unplanned newborns are prone to having low birth weight. Women with unplanned pregnancies have a higher probability of reporting medical problems before and during pregnancy. In fact, the wellbeing of...

Cost effectiveness analysis of plasma genotyping versus tumor genotyping in detection of advanced non-small-cell lung cancer with epidermal growth factor receptor and T790M mutation under the Brazilian private healthcare system perspective

Objective: Comparing the costs and effectiveness of plasma genotyping versus tumor genotyping for detecting the T790M mutation in advanced non-small cell lung cancer (NSCLC) with a mutation in the epidermal growth factor receptor (EGFR) and that progressed after use of an EGFR tyrosine kinase inhibitor (...

Treatment patterns of Hodgkin’s lymphoma in Brazil: experts’ perspective

Background: Hodgkin’s Lymphoma (HL) is a curable type of cancer, with a wide variety of therapies, especially for refractory/relapsing cases. Therefore, the study aims to explore the treatment patterns used in the management of HL patients in Brazil. Methods: A survey was developed to explore the treat...

Unmet needs in multiple myeloma in Brazil from physicians’ perspective – barriers in quality of life and disease management

Objective: There is an increasing trend of the overall survival rates of multiple myeloma (MM) patients over the years, increasing the necessity to improve their quality of life and attenuate unmet medical needs. Therefore, this study aims to explore and describe unmet medical needs and barriers in Brazi...

Hodgkin’s lymphoma unmet medical needs in Brazil: experts’ perspective

Background: In 2016, Hodgkin’s Lymphoma (HL) was responsible for 2,470 new cases in Brazil and, despite recent scientific advances, there are unmet medical needs that affects patients’ outcome. Therefore, we aimed to explore the unmet medical needs in the management of HL patients in Brazil, based on...

Cost-effectiveness and budgetary impact of lipegfilgrastim for the reduction of chemotherapy-induced neutropenia in Brazil

Background: Granulocyte-colony stimulating factors (G-CSFs) reduce the risk of chemotherapy-induced neutropenia. Lipegfilgrastim is a long-acting, once-per-cycle G-CSF, while Brazil’s standard of care is short-acting filgrastim. A cost-effectiveness and budget impact analysis of lipegfilgrastim was con...

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