Resultados: 79

Systematic review of nonpharmacological analgesic interventions for common needle‐related procedure in newborn infants and development of evidence‐based clinical guidelines

Acta paediatr; 106 (6), 2017
The aim of this literature review was to develop clinical guidelines for the prevention and control of needle-related pain in newborn infants. The guidelines were developed by the Italian Society of Neonatology, using the Grading of Recommendations, Assessment, Development and Evaluation approach, based ...

Cost-effectiveness of dengue vaccination in Brazil

Objective: To define the economic value of a tetravalent dengue vaccine in Brazil by estimating the cost-effectiveness vaccine price threshold per dose. Methods: A dengue dynamic transmission model was used to estimate the public health impact of dengue vaccination and related economic parameters. Two va...

Cost-minimization and budget impact analysis of certolizumab pegol for patients with Crohn’s disease, moderate or severe, with relapse after conventional treatment from the perspective of the Brazilian private payer

Objectives: Budget impact and cost-effectiveness analysis are often required by payers when discussing drug reimbursement. We hereby present a cost-minimization (CMA) and budget impact analysis (BIA) regarding the incorporation of certolizumab pegol (CZP) for the treatment of patients with Crohn’s dise...

Hospitalization of schizophrenic patients in the public health system of Minas Gerais, Brazil

Objectives: The aim of this study was to describe the socio-demographic and clinical variables, identify the determinants of length of stay and estimate the cost of inpatient treatment of schizophrenia in Minas Gerais, Brazil. Methods: A non-concurrent cohort was conducted in three psychiatric hospitals ...

Cost-effectiveness of atypical antipsychotics for the treatment of schizophrenia

Objectives: To conduct a cost-effectiveness analysis of second-generation antipsychotics (SGA) for schizophrenia in Brazil. Methods: A Markov model was built for the evaluation of the cost-effectiveness of risperidone, quetiapine, ziprasidone and olanzapine in the Brazilian public health system. The time...

Health-related quality of life in elderly: a review of the EQ-5D use

Objective: To systematically identify and review studies that used EQ-5D to assess health-related quality of life (QoL) in elderly. Methods: Relevant literature was searched in MEDLINE and Lilacs databases and the EuroQol Plenary Meetings Proceedings (June/2003 to June/2013). The inclusion criteria were ...

The Influence of the pact for health on the expenditure on the financing of public health on the view of the Brazilian state

This article measured the dynamics of public health spending, from 2000 to 2015, in the Brazilian States and also in the Federal District. More specifically, it evaluated the effects of the Pact for Health on public health expenditures in all Brazilian States and in the Federal District, from the State o...

Guideline: HLA matching and donor selection for haematopoietic progenitor cell transplantation

Int J Immunogenet; 43 (5), 2016
A review of the British Society for Histocompatibility and Immunogenetics (BSHI) "Guideline for selection and HLA matching of related, adult unrelated donors and umbilical cord units for haematopoietic progenitor cell transplantation" was undertaken by a BSHI appointed writing committee. Literature searc...

Estimation of the potential impact of dengue vaccination on clinical outcomes in Brazil

Objective: The aim of the current analysis was to measure the public health impact of dengue vaccination in Brazil using a published transmission dynamics model. Methods: We adapted a mathematical model that represented the transmission dynamics of the four dengue fever serotypes in humans and in the mos...

Net present value as an instrument to simplificate the decision making process in health technologies economic evaluation

Objectives: The study aims to highlight the Present Value (PV) as a financial analysis tool which could simplify the decision making process of introducing health technologies. The financial evaluation can be extended as necessary, including outcomes and utility. As a model, the instrument was applied to...

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