Resultados: 65

Cost-effectiveness of atypical antipsychotics for the treatment of schizophrenia

Objectives: To conduct a cost-effectiveness analysis of second-generation antipsychotics (SGA) for schizophrenia in Brazil. Methods: A Markov model was built for the evaluation of the cost-effectiveness of risperidone, quetiapine, ziprasidone and olanzapine in the Brazilian public health system. The time...

Health-related quality of life in elderly: a review of the EQ-5D use

Objective: To systematically identify and review studies that used EQ-5D to assess health-related quality of life (QoL) in elderly. Methods: Relevant literature was searched in MEDLINE and Lilacs databases and the EuroQol Plenary Meetings Proceedings (June/2003 to June/2013). The inclusion criteria were ...

Estimation of the potential impact of dengue vaccination on clinical outcomes in Brazil

Objective: The aim of the current analysis was to measure the public health impact of dengue vaccination in Brazil using a published transmission dynamics model. Methods: We adapted a mathematical model that represented the transmission dynamics of the four dengue fever serotypes in humans and in the mos...

Net present value as an instrument to simplificate the decision making process in health technologies economic evaluation

Objectives: The study aims to highlight the Present Value (PV) as a financial analysis tool which could simplify the decision making process of introducing health technologies. The financial evaluation can be extended as necessary, including outcomes and utility. As a model, the instrument was applied to...

Sequential biological therapies in metastatic colorectal cancer (mCRC): a cost comparison analysis for wildtype RAS mCRC patients in Brazil

Objective: To compare the treatment costs of different sequences of regimens including monoclonal antibodies in metastatic colorectal cancer (CRCm) treatment for the Brazilian Supplementary Healthcare System. Methods:  Sixteen scenarios were analyzed, each one comparing a sequence of bevacizumab TML plu...

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